---
title: Genetic Differences Affecting Immunotherapy Response
description: Discover genes and variants that determine patient responses to immunotherapy
image: https://promo.drugdiscoverynews.com/hubfs/TS%20Webinars/Thermo%20December%208th,%202021/December%208th%20webinar/DDN-webinar-Dec-8th_600x316_1_V2.png
---

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Immunotherapy holds great promise for cancer treatment, but why some patients respond better to immunotherapy than others remains a mystery. To uncover the role of genomic heterogeneity in therapeutic efficacy, scientists combine whole genome sequencing of patient samples with machine learning and animal models. In this webinar, Kuan-lin Huang and Benjamin Ostendorf will discuss recent research insights into the contributions of genomic heterogeneity to immunotherapy responses and outcomes.

Topics to be covered

- Predicting tumor immune response using genomic markers and machine-learning
- Determining melanoma progression and therapeutic response with common APOE germline variants

**Speaker Information:**

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Kuan-lin Huang, PhD  
Assistant Professor  
Department of Genetics and Genomic Sciences  
Mount Sinai Center for Transformative Disease Modeling  
Icahn School of Medicine at Mount Sinai

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Benjamin Ostendorf, MD, PhD  
Max Eder Group Leader  
Charité – Universitätsmedizin Berlin

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